Browse the search results

Page 2 of 768
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection

    Balaji Banoth et al.
    The integration of signals via the pleiotropic NF-kappaB (NF-κB) system enables microenvironmental cues to tune cellular responses to pathogenic substances.
    1. Neuroscience

    Acoustic duetting in Drosophila virilis relies on the integration of auditory and tactile signals

    Kelly M LaRue et al.
    Quantitative behavioral assays and modeling show that acoustic duetting in Drosophila during courtship relies on the detection of precisely timed cues via multiple sensory channels.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

    Jerome C Nwachukwu et al.
    Anti-inflammatory effects of resveratrol are mediated by the estrogen receptor to coordinate a complex array of transcriptional coregulators, suggesting that estrogenic effects must be considered in the complex polypharmacology of resveratrol.
    1. Neuroscience

    Midbrain dopamine neurons signal aversion in a reward-context-dependent manner

    Hideyuki Matsumoto et al.
    Dopamine neurons signal value prediction errors (VPEs) integrating information about both reward and aversion, in low reward contexts, whereas VPEs in some dopamine neurons are distorted in high reward contexts.
    1. Neuroscience

    Neural markers of predictive coding under perceptual uncertainty revealed with Hierarchical Frequency Tagging

    Noam Gordon et al.
    The novel neural marker for the integration of top-down predictions and bottom-up signals in perception elucidates uncertainty in perceptual inference and provides evidence for the predictive coding account of perception.
    1. Computational and Systems Biology
    2. Neuroscience

    Integrated systems analysis reveals conserved gene networks underlying response to spinal cord injury

    Jordan W Squair et al.
    Integrating decades of small-scale experiments with human gene expression data provides a systems-level view of the coordinated molecular processes triggered by spinal cord injury, and their relationship to recovery.
    1. Neuroscience

    Reward modulates the effect of visual cortical microstimulation on perceptual decisions

    Nela Cicmil et al.
    Evidence of an interaction between expected reward size and visual cortical microstimulation indicates that expected reward can affect sensory representations.
    1. Developmental Biology
    2. Neuroscience

    Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

    Karina Chaudhari et al.
    Axon repulsion in response to the midline repellent slit depends on an evolutionary conserved interaction between the Roundabout receptor and the wave regulatory complex.
    1. Biochemistry and Chemical Biology

    Fine interaction profiling of VemP and mechanisms responsible for its translocation-coupled arrest-cancelation

    Ryoji Miyazaki et al.
    Time-resolved and site-directed in vivo photo-crosslinking analysis of VemP allows identification of both cis- and trans-elements required for its regulated arrest-cancelation.
    1. Neuroscience

    Breaking down hierarchies of decision-making in primates

    Alexandre Hyafil, Rubén Moreno-Bote
    Computational modeling of behavioral and neural data from monkeys points towards a flat decision-making process in which the brain considers all possible final outcomes simultaneously.