2,106 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

    Erik Lee Snapp et al.
    Signal-peptide cleavage of HIV-1 envelope glycoprotein is delayed because of alpha-helical structure covering the cleavage site, effecting early cleavage alters the folding pathway and resulting in localized misfolding and reduced viral fitness.
    1. Microbiology and Infectious Disease

    Septal secretion of protein A in Staphylococcus aureus requires SecA and lipoteichoic acid synthesis

    Wenqi Yu et al.
    Surface protein precursors traffic to lipoteichoic acid-rich septal membranes of Staphylococcus aureus for cleavage of their YSIRK-GXXS motif signal peptides and SecA-mediated translocation across the plasma membrane.
    1. Structural Biology and Molecular Biophysics

    Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals

    Ho Yee Joyce Fung et al.
    Building on previous work (Fung et al., 2015), the structures of eight new nuclear export signal (NES) peptides bound to Exportin CRM1 are reported, revealing striking diversity in NES structures, a small conserved secondary structural element, and a CRM1 residue that functions as a selectivity filter.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Circadian Rhythms: Feeding time

    Hugh D Piggins , David A Bechtold
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Mechanobiology: A brighter force gauge for cells

    Victor Pui-Yan Ma, Khalid Salaita
    An improved biosensor sheds new light on tension within proteins.
    Insight
    Available as:
    • HTML
    • PDF
    1. Structural Biology and Molecular Biophysics

    Ion Channels: Exploiting natural regulation

    Catherine Proenza
    Using a short peptide to regulate the activity of HCN ion channels illustrates how physiological modulators could inspire new drugs. .
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology

    Reproduction: Shedding light on spawning in jellyfish

    Laurinda A Jaffe
    An opsin receptor has a central role in the production and release of eggs by female jellyfish.
    Insight
    Available as:
    • HTML
    • PDF

Refine your results by:

Type
Research categories