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    1. Neuroscience

    Two long-axis dimensions of hippocampal-cortical integration support memory function across the adult lifespan

    Kristin Nordin, Robin Pedersen ... Alireza Salami
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    A stochastic explanation for observed local-to-global foraging states in Caenorhabditis elegans

    Andrew Margolis, Andrew Gordus
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Cell Biology

    Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos

    Ryan M Finnerty, Daniel J Carulli ... Wipawee Winuthayanon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors

    Joseph Clayton, Aarion Romany ... Jana Shen
    BRAF inhibitors achieve monomer or dimer selectivity through their ability to modulate dimerization and allosteric communication.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Synthetic gene circuits that selectively target RAS-driven cancers

    Gabriel Senn, Leon Nissen, Yaakov Benenson
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary

    Dilara N Anbarci, Jennifer McKey ... Blanche Capel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9

    Wencong Lyu, Haochen Wang ... Wei Tao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Physics of Living Systems

    Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal Model

    Mohammad E Torki, Fan Liu ... Zi Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Glucokinase activity controls peripherally located subpopulations of β-cells that lead islet Ca2+ oscillations

    Erli Jin, Jennifer K Briggs ... Matthew J Merrins
    3D light-sheet imaging identifies the location and metabolic sensitivity of β-cell subpopulations that lead and coordinate islet Ca2+ oscillations.
    1. Cell Biology

    Ezrin defines TSC complex activation at endosomal compartments through EGFR–AKT signaling

    Giuliana Giamundo, Daniela Intartaglia ... Ivan Conte
    Ezrin controls endo-lysosomal signaling by maintaining TSC inhibition through EGFR signaling, activating mTORC1, and inhibiting lysosomal function, unveiling a critical endosome–lysosome network essential for autophagy and cellular homeostasis.
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