The animal phylogeny of glutamate receptors indicates that vertebrate types do not account for all receptor classes originated during evolution, neither are they the pinnacle of a linear evolutive process.

Single-cell tracking and cell-fate simulation suggest that low levels of p53 suppress aneuploid cell formation in unstressed cells and also reveal the dual fate of cells lacking p53 in the presence of p53-proficient cells.

The functional network of β-cells in the pancreatic islet, which has been used to identify important subpopulations of β-cells implicated in diabetes progression, is indicative of intrinsic dynamics rather than structural communication, implying islet robustness.

The HOXA9 reporter and genetic screens facilitated the functional interrogation of the HOXA9 regulome and advanced our understanding of the molecular regulation network in HOXA9-driven leukemia.

The actomyosin network and phospho-regulation combine to polarize fate determinants at the Drosophila neuroblast cell cortex.

By recording simultaneous spike trains from fear-responsive basal amygdala (BA) and place-responsive dorsal hippocampus (dHPC) neurons in rats foraging for food in a risky predatory situation, a novel BA-dHPC circuit coding mechanism for interfacing danger and place information was revealed.

Modelling differential roles for identified dopaminergic and output neurons of the fruit fly mushroom bodies, combined with a novel dopaminergic plasticity rule, explains neural and behavioural phenomena in olfactory learning tasks.

The calcium-binding proteins synaptotagmin 7 and Doc2α act sequentially during asynchronous neurotransmitter release.

A minus-end-binding stabilizes minus-end-out microtubules in dendrites, which are required for dendrite-specific pruning during neuronal remodelling.

An in-depth metagenomic analysis of possibly the most abundant and widespread microbial lineage in the surface ocean teases apart evolutionary processes that maintain its genomic heterogeneity and biogeography.