798 results found
    1. Neuroscience

    Attentional modulation of neuronal variability in circuit models of cortex

    Tatjana Kanashiro, Gabriel Koch Ocker ... Brent Doiron
    Attention reduces noise correlations through enhancing inhibitory feedback in cortical networks.
    1. Neuroscience

    Cerebellum encodes and influences the initiation, performance, and termination of discontinuous movements in mice

    Michael A Gaffield, Britton A Sauerbrei, Jason M Christie
    The activity of cerebellar Purkinje cells both represents and participates in organizing the temporal structure of a periodically performed motor action.
    1. Biochemistry and Chemical Biology

    Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

    Byungchul Kim, Yen-Chih Wang ... Howard C Hang
    Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.
    1. Physics of Living Systems

    Effects of growth feedback on adaptive gene circuits: A dynamical understanding

    Ling-Wei Kong, Wenjia Shi ... Ying-Cheng Lai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Fast-spiking GABA circuit dynamics in the auditory cortex predict recovery of sensory processing following peripheral nerve damage

    Jennifer Resnik, Daniel B Polley
    Dynamic regulation of feedforward inhibition from parvalbumin-expressing inhibitory neurons is linked to the gradual restoration of cortical sensory processing following auditory nerve damage.
    1. Neuroscience

    Learning improves decoding of odor identity with phase-referenced oscillations in the olfactory bulb

    Justin Losacco, Daniel Ramirez-Gordillo ... Diego Restrepo
    Tetrode recordings show that the amplitude of gamma oscillations encodes for information on contextual odorant identity when observed at the peak phase of the theta oscillation in the olfactory bulb.
    1. Neuroscience

    Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus

    Zhigang Shi, Nicole E Pelletier ... Virginia L Brooks
    Leptin acts in the paraventricular nucleus to slowly increase sympathetic nerve activity to skeletal muscle and brown adipose tissue via induction of its own receptor in TRH glutamatergic neurons.
    1. Computational and Systems Biology
    2. Developmental Biology

    A quantitative modelling approach to zebrafish pigment pattern formation

    Jennifer P Owen, Robert N Kelsh, Christian A Yates
    A mathematical modelling approach to understanding zebrafish stripe pattern formation exemplifies a biological rule-set sufficient to generate wild-type and a diverse range of mutant patterns.
    1. Neuroscience

    Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem

    Zahra Khodadadi, Daniel Trpevski ... Jeanette Hellgren Kotaleski
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Determining the effects of paternal obesity on sperm chromatin at histone H3 lysine 4 tri-methylation in relation to the placental transcriptome and cellular composition

    Anne-Sophie Pepin, Patrycja A Jazwiec ... Sarah Kimmins
    Epigenomic and transcriptomic analysis reveals that paternal obesity influences sperm histone H3 lysine 4 tri-methylation enrichment and placenta gene expression, which in turn negatively impact its development and function in a manner that may contribute to metabolic disease in offspring.

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