Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.
An atomic model of the bacterial chemosensory array obtained through the synthesis of cryo-electron tomography and large-scale molecular-dynamics simulations reveals a new kinase conformation during signaling events.
A general machine learning scheme for integrating time-series data from single-molecule experiments and molecular dynamics simulations is proposed and successfully demonstrated for the folding dynamics of the WW domain.
By letting users build interactive simulations directly in a web browser, Artistoo unlocks new ways to communicate, teach, and collaborate in computational biology research.
Direct in-vivo measurements in the human brain test validity of detailed computational models of trancranial electric stimulation and show that electric fields in the brain are weaker than currently assumed.
Optogenetic and electrical low-frequency stimulation in the sclerotic hippocampus prevents the emergence of spontaneous focal and evoked generalized seizures in a mouse epilepsy model.
Molecular simulations, small-angle X-ray and neutron scattering experiments and previously measured NMR experiments were combined to study the structure and dynamics of the proteins and lipids in a nanodisc.
A cellular-level in vivo investigative method that provides unprecedented insights into the dynamics of neuronal activities evoked by transcranial magnetic stimulation.
Studying the activity of cortical neurons in rats reveals the subcellular effects of transcranial magnetic stimulation, which is used for the non-invasive treatment of a variety of brain disorders.
