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Page 4 of 1,017
    1. Computational and Systems Biology

    A three filament mechanistic model of musculotendon force and impedance

    Matthew Millard, David W Franklin, Walter Herzog
    Benchmark simulations show that the VEXAT muscle model is more accurate than a Hill-type muscle model at mimicking the response of biological muscle to length changes great and small.
    1. Genetics and Genomics

    Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations

    M Elise Lauterbur, Maria Izabel A Cavassim ... Ilan Gronau
    Stdpopsim, a framework for generating realistic chromosome-scale simulations, is expanded to facilitate simulations for non-model species, resulting in insights into how such simulations should be designed.
    1. Medicine
    2. Neuroscience

    Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional MRI

    Gen Li, Binshi Bo ... Xiaojie Duan
    Electrical stimulation at the lateral habenula causes an instantaneous remission of depressive symptoms in two rat models, with more medial stimulation sites exhibiting greater antidepressant effects than more lateral stimulation sites, as revealed by functional MRI studies.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Bias in nutrition-health associations is not eliminated by excluding extreme reporters in empirical or simulation studies

    Nao Yamamoto, Keisuke Ejima ... Andrew W Brown
    Elimination of extreme reporters using Goldberg cutoffs does not always produce unbiased estimates of associations between nutrition intakes and health outcomes.
    1. Neuroscience

    Efficient recognition of facial expressions does not require motor simulation

    Gilles Vannuscorps, Michael Andres, Alfonso Caramazza
    It is possible to account for efficient facial expression recognition without having to invoke a mechanism of motor simulation, even in very sensitive and challenging tasks.
    1. Structural Biology and Molecular Biophysics

    On the importance of statistics in molecular simulations for thermodynamics, kinetics and simulation box size

    Vytautas Gapsys, Bert L de Groot
    The use of adequate statistics is demonstrated to be an essential prerequisite to derive conclusions on thermodynamics and kinetics from molecular simulations.
    1. Neuroscience

    Sensory restoration by epidural stimulation of the lateral spinal cord in upper-limb amputees

    Santosh Chandrasekaran, Ameya C Nanivadekar ... Lee E Fisher
    Cervical spinal cord stimulation evokes sensory percepts in the missing hand and arm of people with upper-limb amputation, regardless of amputation level or time post-amputation.
    1. Neuroscience

    Closed-loop auditory stimulation method to modulate sleep slow waves and motor learning performance in rats

    Carlos G Moreira, Christian R Baumann ... Daniela Noain
    Delivery of auditory triggers as unique slow waves-targeting approach yields efficient, stable, and precise modulation of slow-wave activity in rats.
    1. Neuroscience

    Ventromedial prefrontal cortex stimulation enhances memory and hippocampal neurogenesis in the middle-aged rats

    Albert Liu, Neeraj Jain ... Lee Wei Lim
    High-frequency stimulation of the ventromedial prefrontal cortex, which enhances memory and hippocampal neurogenesis, is a novel target for treatment of dementia-related diseases.
    1. Medicine
    2. Neuroscience

    Lead-OR: A multimodal platform for deep brain stimulation surgery

    Simón Oxenford, Jan Roediger ... Andreas Horn
    Lead-OR visualizes results derived from microelectrode recordings in anatomical space, together with information derived from patient-specific MRI data, as well as high-resolution atlas resources during deep brain stimulation surgery.