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    1. Developmental Biology

    Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

    Adriana K Alexander, Karina F Rodriguez ... Humphrey Hung-Chang Yao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features

    Dominic WH Shayler, Kevin Stachelek ... David Cobrinik
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Species and cell-type properties of classically defined human and rodent neurons and glia

    Xiao Xu, Elitsa I Stoyanova ... Nathaniel Heintz
    Gene expression and epigenetic profiling of defined cell types in the central nervous system of mouse, rat, and human reveals inter-species and inter-individual differences.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

    Man Zhu, Meng Ma ... Jing Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Developmental Biology
    2. Genetics and Genomics

    Integration of ATAC and RNA-sequencing identifies chromatin and transcriptomic signatures in classical and non-classical zebrafish osteoblasts and indicates mechanisms of entpd5a regulation

    Kleio Petratou, Martin Stehling ... Stefan Schulte-Merker
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    • Convincing
    1. Neuroscience

    History-dependent spiking facilitates efficient encoding of polarization angles in neurons of the central complex

    Lisa Rother, Anna Stöckl, Keram Pfeiffer
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Neuroscience

    MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment

    Flavio H Beraldo, Daniel Palmer ... Marco AM Prado
    Comprehensive dataset of high-level cognitive assessment in mouse models of neurodegeneration, accompanied by an open-access database/repository to change the paradigm of how cognitive studies in animal models can be shared/re-used.
    1. Neuroscience

    Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C1C2B region

    Marcial Camacho, Bradley Quade ... Christian Rosenmund
    Two different binding modes of the Munc13-1 C­1C2B region govern synaptic vesicle priming and neurotransmitter release probability.
    1. Developmental Biology
    2. Genetics and Genomics

    Transcriptional control of compartmental boundary positioning during Drosophila wing development

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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