In this episode, we hear about why we always have space for dessert, how collecting seeds from large areas could help restoration projects, gut bacteria, the placebo effect and toxoplasmosis.
In the first eLife podcast we hear about the origins of multicellularity, the Irish potato famine, hepatitis viruses, how fog affects the behaviour of car drivers, and the evolution of chromatin.
In this episode we hear about controlling sperm by optogenetics, hibernation, body clocks, enzyme structure, and a way to overcome stress-induced infertility.
TRAF3, a negative regulator of noncanonical NF-κB signaling, maintains epithelial cell quiescence at confluence, and its loss triggers upregulation of immunity genes and prevents entry into G0 at high cell density.
Morphologic, molecular, biomechanical and computational analyses show that the specialized extracellular matrix architecture of the umbilical artery contributes to its rapid closure at birth and regulates smooth muscle cell differentiation.
Inhibition of bacterial protein synthesis by an antimicrobial peptide apidaecin triggers translation arrest at the stop codons, ribosome queuing and pervasive stop codon readthrough.
Genome-wide redistribution of KLF5 binding leads to activation of a cell cycle gene expression programme and proliferation control in oesophageal cancer.
Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.
TRPV4 channels in brain capillaries are suppressed by the phosphoinositide PIP2 and activated by receptor agonists implicated in neurovascular coupling.
