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Ion channels: A Collection of Articles
Edited by Kenton J Swartz et al.
eLife has published papers on topics related to the molecular structure and functional mechanisms of a diverse array of ion channel proteins.
Episode 45: February 2018
In this episode, we hear about disease control in insects, placental development, post-traumatic stress disorder, the mission to create a human cell atlas and how crickets amplify their song.
Episode 17: January 2015
In this episode we hear about controlling sperm by optogenetics, hibernation, body clocks, enzyme structure, and a way to overcome stress-induced infertility.
Episode 75: July 2021
In this episode, we hear about the cost of high status, vaccine trackers, pain relief in newborns, Alzheimer's disease and how losing a partner can increase the risk of cancer.
Chromosomes and Gene Expression
Aging, Geroscience and Longevity: A Special Issue
Edited by Matt Kaeberlein et al.
eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of aging and interventions that extend longevity.
Stem Cells and Regenerative Medicine
Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the
Lisa Zipper et al.
A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of
Sexual dimorphism in trait variability and its eco-evolutionary and statistical implications
Susanne RK Zajitschek et al.
Sex differences in trait variability imply that both sexes should be included in biomedical trials, using sex-specific statistical power calculations.
Immunology and Inflammation
BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages
Jie Li et al.
Phosphorylation-mediated inactivation of pro-apoptotic BCL-2 family protein BAD confers the apoptosis resistance on synovial sublining macrophages, thereby contributing to the development of rheumatoid arthritis.
is a haploinsufficient tumor suppressor that limits telomere length
Isabelle Schmutz et al.
Mutations in TIN2, a component of shelterin that keeps telomere length in check, lead to cancer-predisposition by disabling the telomere tumor suppressor pathway.
Learning speed and detection sensitivity controlled by distinct cortico-fugal neurons in visual cortex
Sarah Ruediger, Massimo Scanziani
Neural pathways from mammalian visual cortex to ancestral brain structures control learning speed and performance of a simple detection task.
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