7,428 results found
    1. Genetics and Genomics

    RETRACTED: Amino acid synthesis loss in parasitoid wasps and other hymenopterans

    Xinhai Ye, Shijiao Xiong ... Fei Li
    The synthesis capability of some amino acids is lost during the insect evolution, and hymenopteran parasitoids can make up for these deficiencies by altering free amino acid concentrations in host.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

    Iris Jonkers, Hojoong Kwak, John T Lis
    The elongation rate of RNA Polymerase II varies greatly between and along genes, as this enzyme accelerates from stable pausing to rapid elongation within genes, and is influenced by CG-content, exons and chromatin.
    1. Evolutionary Biology

    Metabolic co-dependence drives the evolutionarily ancient Hydra–Chlorella symbiosis

    Mayuko Hamada, Katja Schröder ... Thomas CG Bosch
    The symbiotic relationship between Hydra and Chlorella is driven by metabolic co-dependence and characterized by changes in the photobiont genome in terms of lack of genes essential in free-living algae.
    1. Cancer Biology

    Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

    Zeyad D Nassar, Chui Yan Mah ... Lisa M Butler
    DECR1, a rate-limiting enzyme for polyunsaturated fatty acid (PUFA) β-oxidation, is an androgen-repressed gene in prostate cancer cells that limits oxidative stress to promote cancer cell survival.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

    Damien Detraux, Marino Caruso ... Patricia Renard
    Accumulation of succinate during the in vitro modeling of embryonic stem cell state transition critically regulate cell fate.
    1. Cell Biology

    Endoplasmic reticulum tubules limit the size of misfolded protein condensates

    Smriti Parashar, Ravi Chidambaram ... Susan Ferro-Novick
    The endoplasmic reticulum (ER) uses ER tubules and specific ER autophagy machinery to prevent toxic, dominant-interfering, disease-causing, mutant proteins from entering the secretory pathway.
    1. Neuroscience

    Tracking the relation between gist and item memory over the course of long-term memory consolidation

    Tima Zeng, Alexa Tompary ... Sharon L Thompson-Schill
    Human learners’ memory for generalities across individual items biased memory for these items after 1 month.
    1. Cancer Biology
    2. Cell Biology

    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion

    Akikazu Harada, Shinji Matsumoto ... Akira Kikuchi
    Specific localization of KRAS downstream target ARL4C with its novel interacting proteins was the active site of invasion of pancreatic cancer cell and induced metastasis.
    1. Neuroscience

    Rhodopsin targeted transcriptional silencing by DNA-binding

    Salvatore Botta, Elena Marrocco ... Enrico Maria Surace
    Photoreceptor genomic binding of a 20 base-pair-long DNA sequence by a synthetic DNA-binding protein turns off Rhodopsin expression.
    1. Evolutionary Biology

    Late-life fitness gains and reproductive death in Cardiocondyla obscurior ants

    Luisa Maria Jaimes-Nino, Jürgen Heinze, Jan Oettler
    Lifelong continuous reproduction, late-life investment into female sexuals, a short phase of senescence, and reproductive death characterize the life history of Cardiocondyla obscurior ant queens.

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