4,074 results found
    1. Neuroscience

    Ventrolateral periaqueductal gray neurons prioritize threat probability over fear output

    Kristina M Wright, Michael A McDannald
    Single-unit activity in the ventrolateral periaqueductal gray, a brain region implicated in organizing fear output, is found to reflect threat probability, a more versatile threat signal.
    1. Neuroscience

    Uniting functional network topology and oscillations in the fronto-parietal single unit network of behaving primates

    Benjamin Dann et al.
    Oscillatory synchronized hub neurons coordinate neural network activity across multiple brain areas.
    1. Neuroscience

    Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation

    Rosa Maria Sanchez Panchuelo et al.
    The combination of intraneural microstimulation and 7T fMRI makes it possible to bridge the gap between first-order mechanoreceptive afferent input codes and their spatial, dynamic and perceptual representations in human cortex.
    1. Neuroscience

    Active avoidance requires inhibitory signaling in the rodent prelimbic prefrontal cortex

    Maria M Diehl et al.
    Avoiding danger requires inhibitory signaling in the prelimbic prefrontal cortex, as evidenced by optogenetic manipulations based on neuronal firing patterns.
    1. Neuroscience

    Orbitofrontal neurons signal sensory associations underlying model-based inference in a sensory preconditioning task

    Brian F Sadacca et al.
    Neural activity in the orbitofrontal cortex (OFC) represents incidental stimulus-stimulus associations, providing additional evidence for OFC having a role in cognition beyond functions centered on processing value or biological significance.
    1. Neuroscience

    Phasic and tonic neuron ensemble codes for stimulus-environment conjunctions in the lateral entorhinal cortex

    Maryna Pilkiw et al.
    Neuron populations in the lateral entorhinal cortex discriminate between memory-based contexts through both continuous "tonic" activity patterns as well as by their stimulus-evoked "phasic" responses.
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Computational and Systems Biology
    2. Neuroscience

    Cell assemblies at multiple time scales with arbitrary lag constellations

    Eleonora Russo, Daniel Durstewitz
    A novel statistical algorithm for mining high-dimensional spike train (count) data for significant spatio-temporal patterns reveals new insights into task and brain area dependent functional organization of neural activity.
    1. Neuroscience

    Midbrain dopamine neurons compute inferred and cached value prediction errors in a common framework

    Brian F Sadacca et al.
    Midbrain dopamine neurons in rats signal discrepancies between predicted and actual rewards, regardless of whether the rewards are predicted on the basis of experience or inference.
    1. Neuroscience

    Orbitofrontal neurons acquire responses to ‘valueless’ Pavlovian cues during unblocking

    Michael A McDannald et al.
    Orbitofrontal cortex neurons fire in response to cues with no value independent of what can be inferred through features of the predicted outcome.

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