David Trombley McSwiggen, Helen Liu ... Hilary P Beck
Single-molecule tracking at scale, analyzing millions of cells and thousands of compounds per day, demonstrates that measuring protein motion provides mechanistic insights relevant to drug discovery.
Bethany M Bartlett, Yatendra Kumar ... Wendy A Bickmore
Evidence is provided suggesting that heterochromatin re-organisation during cell senescence can compromise the structural integrity of the nucleus, leading to activation of an inflammatory process.