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    1. Neuroscience

    Instantaneous movement-unrelated midbrain activity modifies ongoing eye movements

    Antimo Buonocore, Xiaoguang Tian ... Ziad M Hafed
    Sensory activity within the superior colliculus is read out by downstream motor structures and contributes to individual saccade kinematics with single spike precision.
    1. Developmental Biology
    2. Evolutionary Biology

    An epithelial signalling centre in sharks supports homology of tooth morphogenesis in vertebrates

    Alexandre P Thiery, Ariane SI Standing ... Gareth J Fraser
    The development of diverse tooth shapes among vertebrates, from sharks to mammals, is a highly conserved process, utilising a similar dental signalling centre for more than 400 million years.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Soil-borne fungi alter the apoplastic purinergic signaling in plants by deregulating the homeostasis of extracellular ATP and its metabolite adenosine

    Christopher Kesten, Valentin Leitner ... Clara Sanchez-Rodriguez
    Biochemical and in vivo physiology imaging reveal that plant pathogens actively imbalance the apoplastic eAdo/eATP levels as a virulence mechanism.
    1. Structural Biology and Molecular Biophysics

    Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement

    Avinash B Patel, Camille M Moore ... Eva Nogales
    The structure of the yeast RSC complex, a member of the SWI/SNF chromatin remodeling family, determined by cryo-electron microscopy, reveals a conserved structural core and the mode of nucleosome engagement.
    1. Neuroscience

    Role of the postinspiratory complex in regulating swallow–breathing coordination and other laryngeal behaviors

    Alyssa Huff, Marlusa Karlen-Amarante ... Jan-Marino Ramirez
    The postinspiratory complex acts as an interface between the swallow pattern generator and the preBötzinger complex to coordinate swallow and breathing.
    1. Cancer Biology
    2. Cell Biology

    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion

    Akikazu Harada, Shinji Matsumoto ... Akira Kikuchi
    Specific localization of KRAS downstream target ARL4C with its novel interacting proteins was the active site of invasion of pancreatic cancer cell and induced metastasis.
    1. Neuroscience

    Amygdala-ventral striatum circuit activation decreases long-term fear

    Susana S Correia, Anna G McGrath ... Ki A Goosens
    Behavior- or optogenetic-driven activation of a basolateral amygdala projection to the nucleus accumbens enhances infralimbic cortex activity and long-term fear extinction.
    1. Evolutionary Biology
    2. Neuroscience

    Convergent mosaic brain evolution is associated with the evolution of novel electrosensory systems in teleost fishes

    Erika L Schumacher, Bruce A Carlson
    In teleost fishes, the independent evolution of electrosensory systems was repeatedly associated with evolutionary changes in brain region scaling that were independent of changes in brain–body allometry.
    1. Neuroscience

    The locus coeruleus broadcasts prediction errors across the cortex to promote sensorimotor plasticity

    Rebecca Jordan, Georg B Keller
    A brain-wide neuromodulatory system enables rapid cortical plasticity to occur by signaling sensorimotor prediction errors across wide regions of the cerebral cortex.
    1. Neuroscience

    Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

    Hala Harony-Nicolas, Maya Kay ... Joseph D Buxbaum
    The production, validation and study of a novel rat model for Phelan McDermid Syndrome shows an ameliorative effect of oxytocin on both social and attentional deficits.