1,849 results found
    1. Medicine
    2. Neuroscience

    Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling

    Sachin Sharma, Russell Littman ... Olujimi A Ajijola
    Cardiac-specific neurons residing in stellate ganglia comprised of three subsets of neurons based upon their transcriptomic and neurochemical properties and modulates cardiac sympathetic control.
    1. Neuroscience

    The landscape of regulatory genes in brain-wide neuronal phenotypes of a vertebrate brain

    Hui Zhang, Haifang Wang ... Jie He
    Single-cell transcriptomes of larval zebrafish whole brain shed light on the multidimensional landscapes of transcription factors and post-transcriptional regulators in vertebrate whole-brain neuronal classification and revealed principles of how neuronal cell diversity develops and evolves.
    1. Neuroscience

    Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

    Isaac M Chiu, Lee B Barrett ... Clifford J Woolf
    Molecular analysis paints a detailed picture of the distinctiveness and complexities of peripheral somatosensory neurons.
    1. Immunology and Inflammation

    Single-cell RNA sequencing unveils the hidden powers of zebrafish kidney for generating both hematopoiesis and adaptive antiviral immunity

    Chongbin Hu, Nan Zhang ... Jian-zhong Shao
    scRNA-seq revealed the fish kidney is a dual-functional entity with functionalities of both primary and secondary lymphoid organs and highlighted the multifaced biology of kidney in ancient vertebrates.
    1. Developmental Biology

    Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration

    Ke-Hsuan Wei, I-Ting Lin ... Shih-Lei (Ben) Lai
    An extensive characterization of inflammatory cell dynamics, function, and potential interaction during zebrafish cardiac repair identified specific resident macrophage subsets function in debris clearance, inflammatory resolution, and extracellular matrix remodeling, indispensable for successful heart regeneration.
    1. Developmental Biology

    Two FGFRL-Wnt circuits organize the planarian anteroposterior axis

    M Lucila Scimone, Lauren E Cote ... Peter W Reddien
    Single-cell RNA sequencing identifies an adult regional gene expression map in planarian muscle that includes two FGFRL-Wnt circuits controlling head and trunk tissue pattern.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Profiling the bloodstream form and procyclic form Trypanosoma brucei cell cycle using single-cell transcriptomics

    Emma M Briggs, Catarina A Marques ... Keith R Matthews
    Single-cell transcriptomics of cryopreserved parasites reveals extensive cyclic regulation of mRNA abundance by Trypanosoma brucei during the cell cycle.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates

    Adele Francis Xu, Rut Molinuevo ... Maria Barna
    Ribosomal proteins Rps27 (eS27) and Rps27l (eS27L) are an ancient pair of duplicated genes that encode functionally interchangeable proteins, yet have been evolutionarily retained because both copies are necessary to achieve protein expression across cell types.
    1. Cancer Biology

    Molecular classification and tumor microenvironment characteristics in pheochromocytomas

    Sen Qin, Yawei Xu ... Zheng Zhang
    ScRNA-seq of diverse pheochromocytoma patients reveals distinct microenvironment characteristics and supports an informative molecular classification system.
    1. Developmental Biology
    2. Neuroscience

    Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

    Tuo Shi, Marielle O Beaulieu ... David W Raible
    Single-cell transcriptomic analysis defines hair cell and supporting cell types in the zebrafish inner ear, and reveals homologies with cells in the mammalian ear.

Refine your results by:

Type
Research categories