4,161 results found
    1. Neuroscience
    2. Physics of Living Systems

    Unsupervised Bayesian Ising Approximation for decoding neural activity and other biological dictionaries

    Damián G Hernández, Samuel J Sober, Ilya Nemenman
    The proposed method deciphers which low-level patterns (such as spikes) control high-level features (behavior) in relative small biological datasets, taking into account the statistical dependencies between such patterns.
    1. Microbiology and Infectious Disease

    A qnr-plasmid allows aminoglycosides to induce SOS in Escherichia coli

    Anamaria Babosan, David Skurnik ... Thomas Guillard
    A mechanism whereby aminoglycosides-mediated SOS induction in Escherichia coli also promote high-level fluoroquinolone resistance.
    1. Cancer Biology

    Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunities

    Honglei Zhang, Chao Liu ... Gaofeng Li
    MAD1 and TPRN were identified as novel potential therapeutic targets of lung adenocarcinoma in female never-smokers from the Xuanwei area.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium

    David R Hill, Sha Huang ... Jason R Spence
    Contact with bacteria and subsequent hypoxia promotes functional maturation of the immature gastrointestinal tract.
    1. Neuroscience

    VEGF signaling regulates the fate of obstructed capillaries in mouse cortex

    Patrick Reeson, Kevin Choi, Craig E Brown
    Mapping the fate of clogged brain capillaries reveals that VEGF signaling plays a critical role in dictating whether capillaries regain blood flow and persist or are pruned from the vascular tree.
    1. Medicine

    Deletion of FNDC5/irisin modifies murine osteocyte function in a sex-specific manner

    Anika Shimonty, Fabrizio Pin ... Lynda F Bonewald
    Analysis of mice lacking the precursor for irisin, FNDC5, provides evidence for a sex-specific role of irisin in calcium release from bone due to osteocytic osteolysis.
    1. Computational and Systems Biology

    Estimating the protein burden limit of yeast cells by measuring the expression limits of glycolytic proteins

    Yuichi Eguchi, Koji Makanae ... Hisao Moriya
    Measurement of expression limits of yeast glycolytic proteins reveal the protein burden limit, which is the expression limit of any protein in the cell.
    1. Developmental Biology
    2. Genetics and Genomics

    Genome-wide errant targeting by Hairy

    Kurtulus Kok, Ahmet Ay ... David N Arnosti
    Pervasive ‘futile cycling’ by chromatin-modifying factors suggests a mechanism for creating new links in gene regulatory networks.
    1. Developmental Biology
    2. Neuroscience

    Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors

    Gerrit Cornelis Beekhof, Catarina Osório ... Martijn Schonewille
    Different Purkinje cell subpopulations show distinct developmental profiles of physiological activity, climbing fiber inputs and axonal and dendritic morphology, matching different timelines of cerebellum-dependent behaviors.
    1. Developmental Biology
    2. Evolutionary Biology

    Decoupling from yolk sac is required for extraembryonic tissue spreading in the scuttle fly Megaselia abdita

    Francesca Caroti, Everardo González Avalos ... Steffen Lemke
    Extraembryonic tissue spreading in the scuttle fly Megaselia abdita requires mechanical decoupling from the underlying yolk sac.

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