The axial organization and dynamics of the HOPS complex at membrane surface are resolved by graphene-induced energy transfer with subnanometer resolution.
Alexander Borodavka, Eric C Dykeman ... Don C Lamb
In rotaviruses, the selective packaging of eleven distinct genomic RNA segments requires virus-encoded protein NSP2 to alter the RNA structures, facilitating their interactions with each other.
Julianne M Troiano, Federico Perozeni ... Gabriela S Schlau-Cohen
Light-harvesting complex stress-related is a protein from photosynthetic green algae that prevents damage from sunlight via two distinct conformational processes, which protect against different timescales of solar fluctuations.
Víctor M Hernández-Rocamora, Natalia Baranova ... Waldemar Vollmer
The synthesis of bacterial cell wall peptidoglycan was reconstituted in lipid bilayers and detected by a novel Förster resonance energy transfer real-time assay.
Diffusivity, extracellular interactions of Nodal ligands with the receptors and inhibitors, and selective ligand destruction collectively shape the Nodal morphogen gradient.
The mechanical stability of a nucleosome is enhanced upon the introduction of a single base pair mismatch that makes DNA more bendable, with implications on mismatch repair in vivo.
Andrew S LaCroix, Andrew D Lynch ... Brenton D Hoffman
A quantitative understanding of molecular tension sensor function enables the production of unique sensors with desired mechanical properties as well as the ability to distinguish between protein force and protein deformation in mechanosensitive processes.