Cytological and biochemical analyses reveal Arabidopsis formin 2 is involved in regulating PD permeability by anchoring actin filaments to PD and stabilizing them through actin filament barbed end capping activity.
A new biophysical model enables the reconciliation of ultrastructural and tissue level measurements on parameters affecting intercellular communication, and provides novel functional insight into experimental findings.
Lipocalin-2 is a strong predictor of hunger scores, reflects an anti-obesity response that is deregulated in severely obese subjects, and exerts an anorexigenic function with a conserved interspecies mechanism.
Dissecting structural, cellular and molecular differences between transplanted and spontaneous mouse tumor models, highlighting their relevance for predicting the efficacy of anti-cancer treatments in patients.
A multipartite virus functionally spreads its distinct genome segments in distinct individual cells of the host plant, and complementation of the viral genes across cells allows a pluricellular infection cycle.
Structure, dynamics, and mutation of a gamete fusion protein and comparisons to viral homologues suggest that after trimerization the domain bearing the membrane-inserting fusion loops can pivot with respect to the trimer 3-fold axis.