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    1. Immunology and Inflammation

    Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

    Dorothy K Sojka et al.
    Natural killer cells that were commonly thought to circulate around the body can actually reside in distinct tissues, such as in the liver, skin or uterus, and do not re-circulate.
    1. Cancer Biology
    2. Cell Biology

    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

    William Putzbach et al.
    Loading of CD95 and CD95L-derived sequences into the RNA-induced silencing complex elicits a distinct form of RNAi-mediated cell death of cancer cells that results from the targeting of multiple survival genes.
    1. Immunology and Inflammation

    Epidermal RAF prevents allergic skin disease

    Josipa Raguz et al.
    In keratinocytes, the BRAF and RAF1 proteins work independently to balance the activity of mitogenic and stress kinase cascades and uphold the mechanical and immunological barrier functions of the epidermis.
    1. Developmental Biology
    2. Immunology and Inflammation

    The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

    Florian Mair et al.
    Thymic stromal cells help to develop and shape the gamma delta T cell pool.
    1. Neuroscience

    Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

    Gukhan Kim et al.
    A new synaptic scaffold important for neurotransmission and synaptic plasticity has been identified.
    1. Cell Biology

    Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

    Toru Hiratsuka et al.
    In vivo imaging of extracellular signal-regulated kinase activity reveals radial ERK activation patterns that are associated with cell cycle progression in the mouse epidermis.