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    1. Genetics and Genomics
    2. Neuroscience

    Identification of a molecular basis for the juvenile sleep state

    Leela Chakravarti Dilley et al.
    Pdm3, a transcription factor, coordinates an early developmental program that prepares the brain to later execute high levels of juvenile adult sleep.
    1. Neuroscience

    An open-source, high-performance tool for automated sleep staging

    Raphael Vallat, Matthew P Walker
    A robust automatic sleep-staging algorithm offers a high level of accuracy matching that of typical human interscorer agreement.
    1. Neuroscience

    Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

    Xiang-Shan Yuan et al.
    Rostral and central striatum controls slow-wave sleep during active phase in mice.
    1. Cell Biology
    2. Neuroscience

    Short and long sleeping mutants reveal links between sleep and macroautophagy

    Joseph L Bedont et al.
    Unbiased and targeted genetic approaches reveal a link between sleep and autophagy that could be relevant for sleep function, and for understanding pathological consequences of chronic sleep loss.
    1. Computational and Systems Biology
    2. Neuroscience

    Blood transcriptome based biomarkers for human circadian phase

    Emma E Laing et al.
    An unbiased modelling approach shows that only a few blood transcriptome samples are required to accurately assess the human circadian melatonin phase, even during altered sleep schedules.
    1. Neuroscience

    Sleep-active neuron specification and sleep induction require FLP-11 neuropeptides to systemically induce sleep

    Michal Turek et al.
    The mechanisms of specification and sleep induction by the single sleep-active neuron are revealed in C. elegans.
    1. Neuroscience

    Sleep spindles mediate hippocampal-neocortical coupling during long-duration ripples

    Hong-Viet Ngo et al.
    Triggered by (long-duration) hippocampal ripples, spindles facilitate communication between the hipppocampus and neocortex during natural sleep.
    1. Neuroscience

    Coupling between motor cortex and striatum increases during sleep over long-term skill learning

    Stefan M Lemke et al.
    Sleep spindles, distinctive brain activity patterns occurring in non-REM sleep, modify cross-area connectivity in the motor network relevant for behavioral flexibility, impacting subsequent behavior.
    1. Neuroscience

    Neurovascular coupling and bilateral connectivity during NREM and REM sleep

    Kevin L Turner et al.
    Sleep-related hemodynamic signals are much larger than those in the awake brain, so it is crucial to monitor the arousal state during studies of spontaneous activity.
    1. Computational and Systems Biology
    2. Neuroscience

    Sub-minute prediction of brain temperature based on sleep–wake state in the mouse

    Yaniv Sela et al.
    The sleep–wake state sequence explains almost all of the variance in brain temperature in the mouse, and its detailed dynamics can be accurately predicted only using sleep–wake information.