aDNA revealed a model of domestication where an ancient guanaco population no longer exists, the loss of the ancient vicuña genetic variation in the modern populations, and frequently interbreeding practices.
Integrons deploy a variety of adaptive strategies including excision, shuffling, and duplication of cassettes that foster rapid bacterial adaptation and resistance evolution while protecting the genomic integrity of the host.
Somatostatin interneurons are novel mediators of serotonergic modulation in entorhinal cortex via activation of 5-HT2A receptors, a receptor involved in the etiology of different psychiatric disorders.
Hippocampal and prefrontal neuronal populations form slow behavioral-timescale (~seconds) and fast cognitive-timescale (~100 ms) sequential activity patterns as theta and replay sequences, which play distinct yet cooperative roles in memory-guided decision-making.
Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.