1,196 results found
    1. Structural Biology and Molecular Biophysics

    Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

    Amanda F Clouser et al.
    Multiple iso-energetic-specific interactions involving the intrinsically-disordered region of sHSP HSPB1 define a quasi-ordered state, providing insights into inherited disease-associated mutations within the region that are thought to be disordered.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis

    Ponni Rajagopal et al.
    Small decreases in pH associated with cellular stress conditions unleash a cryptic mode of client binding in a ubiquitously expressed human small heat shock protein that is more effective at delaying client aggregation.
    1. Ecology

    Endosymbiosis: Gasping for air

    Steven G Ball, Ugo Cenci
    Transcriptomics is shedding new light on the relationship between photosynthetic algae and salamander eggs.
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology
    2. Plant Biology

    Biosensors: Plant biologists FRET over stress

    Won-Gyu Choi, Simon Gilroy
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology

    The Natural History of Model Organisms: An organismal perspective on C. intestinalis development, origins and diversification

    Matthew J Kourakis, William C Smith
    The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.
    1. Ecology

    Thermoregulation: Bugs battle stress from hot blood

    Joshua B Benoit, David L Denlinger
    A heat exchange mechanism in the head of kissing bugs helps to prevent stress and regulate their temperature while they feed on warm blood.
    Insight
    Available as:
    • HTML
    • PDF
  1. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.
    1. Evolutionary Biology

    The Natural History of Model Organisms: Insights into mammalian biology from the wild house mouse Mus musculus

    Megan Phifer-Rixey, Michael W Nachman
    Studies of the house mouse Mus musculus have provided important insights into mammalian biology, and efforts to study wild house mice and to create new inbred strains from wild populations have the potential to increase its usefulness as a model system.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Viral factors in influenza pandemic risk assessment

    Marc Lipsitch et al.
    We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.
    1. Microbiology and Infectious Disease
    2. Ecology

    The Natural History of Model Organisms: The unexhausted potential of E. coli

    Zachary D Blount
    A better understanding of the remarkable diversity, natural history and complex ecology of E. coli in the wild could shed new light on its biology and role in disease, and further expand its many uses as a model organism.

Refine your results by:

Type
Research categories