769 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways

    Fiona J Tooke et al.
    Bioinformatics and experimental approaches identify families of membrane proteins requiring the co-ordinated action of the Sec pathway and Tat pathways for their integration and define features of the polypeptides that mediate interaction with these pathways.
    1. Neuroscience

    Sleep: Shifting memories

    Hong-Viet V Ngo, Bernhard P Staresina
    A region of the brain called the putamen has a central role in memory consolidation during sleep.
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    1. Neuroscience

    Social Chemosignaling: The scent of a handshake

    Gün R Semin, Ana Rita Farias
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    1. Neuroscience

    A social chemosignaling function for human handshaking

    Idan Frumin et al.
    After shaking hands with a stranger, human volunteers often subliminally bring their hand to their nose and sniff it, possibly to collect important olfactory information.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    The allosteric activation of cGAS underpins its dynamic signaling landscape

    Richard M Hooy, Jungsan Sohn
    Rigorous biophysical studies reconcile several conflicting views on how cGAS is activated, and present a new unifying allosteric activation mechanism.
    1. Neuroscience

    Choice history biases subsequent evidence accumulation

    Anne E Urai et al.
    Choice history signals bias the interpretation of current sensory input, akin to shifting endogenous attention toward (or away from) the previously selected interpretation.
  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
    1. Neuroscience

    Neuroscience: Multitasking on the run

    Mary E Hatten, Stephen G Lisberger
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  2. Point of View: Overflow in science and its implications for trust

    Sabina Siebert et al.
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.

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