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    1. Structural Biology and Molecular Biophysics

    Model-based local density sharpening of cryo-EM maps

    Arjen J Jakobi et al.
    Local sharpening of cryo-electron microscopy maps using atomic models can increase the interpretability of densities in cases of resolution variation and facilitates model building and refinement.
    1. Neuroscience

    Sexual dimorphism in striatal dopaminergic responses promotes monogamy in social songbirds

    Kirill Tokarev et al.
    Co-evolution of sexually dimorphic reinforcement systems for song can explain the coexistence of the seemingly contradictory traits of gregariousness and monogamy in social songbirds.
    1. Evolutionary Biology

    Social Evolution: How ants send signals in saliva

    Markus Knaden
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    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Piezo Ion Channels: Portraits of a pressure sensor

    Alexander T Chesler, Marcin Szczot
    Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.
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    1. Cell Biology
    2. Neuroscience

    2018 Gairdner Awards: The past, present and future of light-gated ion channels and optogenetics

    Sheena A Josselyn
    Research into light-gated ion channels called channelrhodospins laid the foundations for the development of optogenetics, a technique that has gone on to revolutionize neuroscience.
    1. Ecology
    2. Evolutionary Biology

    Evolution: Modeling evolutionary transitions in social insects

    Michael Doebeli, Ehab Abouheif
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  1. Point of View: Overflow in science and its implications for trust

    Sabina Siebert et al.
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
    1. Neuroscience

    Connectomics: Think small

    Luis A Bezares-Calderón, Gáspár Jékely
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