369 results found
    1. Computational and Systems Biology
    2. Medicine

    Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

    Hong Yang, Cheng Zhang ... Adil Mardinoglu
    Inhibiting c-Jun N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.
    1. Neuroscience

    Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)

    Mathew D Edwards, Ziwei Yin ... Yoh Isogai
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Medicine
    2. Microbiology and Infectious Disease

    HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

    Karen Giménez-Orenga, Eva Martín-Martínez ... Elisa Oltra
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice

    Alessandro Piccin, Anne-Emilie Allain ... Angelo Contarino
    Both genetic and pharmacological studies reveal an essential role for the CRF1 receptor in social behavior deficits induced by a single morphine administration in male, but not in female, mice.
    1. Neuroscience

    Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity

    Ryo Masumura, Kyosuke Goda ... Naofumi Uesaka
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Ecology

    Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird

    Itai Bloch, David Troupin ... Nir Sapir
    Little Swifts dynamically adjust their foraging behavior to aerial insect abundance, revealing key insights into predator–prey interactions and optimal foraging strategies in aerial environments.
    1. Neuroscience

    Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins

    Sharon Inberg, Yael Iosilevskii ... Benjamin Podbilewicz
    Mechanosensory isolation of C. elegans nematodes independently induces homeostatic structural changes in the dendritic tree and differential response to mechanical stimulation, both these structural and behavioral outcomes are mediated by degenerins and do not affect presynaptic calcium dynamics.
    1. Genetics and Genomics
    2. Neuroscience

    Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation

    Tanya Wolff, Mark Eddison ... Gerald M Rubin
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer’s disease risk genes

    François Kroll, Joshua Donnelly ... Jason Rihel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    The protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway

    Yalan Jiang, Pingping He ... Xiaoou Shan
    Eugenol has the ability to improve the type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway.
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