163 results found
    1. Neuroscience

    Thermosensitive alternative splicing senses and mediates temperature adaptation in Drosophila

    Ane Martin Anduaga, Naveh Evantal ... Sebastian Kadener
    Temperature controls the circadian clock by directly regulating the alternative splicing of timeless..
    1. Neuroscience

    Evolution of neuronal anatomy and circuitry in two highly divergent nematode species

    Ray L Hong, Metta Riebesell ... Ralf J Sommer
    The substrate for evolutionary divergence does not lie in changes in neuronal cell number or targeting, but rather in sensory perception and synaptic partner choice within invariant, prepatterned neuronal processes.
    1. Neuroscience

    Evidence for embracing normative modeling

    Saige Rutherford, Pieter Barkema ... Andre F Marquand
    A brain chart database, containing functional and structural normative models, was tested to compare normative modeling features to raw features across three benchmarking tasks including group difference testing, classification, and regression.
    1. Neuroscience

    Body size as a metric for the affordable world

    Xinran Feng, Shan Xu ... Jia Liu
    The human body shapes how we perceive and interact with the environment, with body size serving as a boundary for defining potential actions, hereby enlightening research on foundation agents.
    1. Neuroscience

    Motor context dominates output from purkinje cell functional regions during reflexive visuomotor behaviours

    Laura D Knogler, Andreas M Kist, Ruben Portugues
    Purkinje cells of the cerebellum, a conserved vertebrate brain region important for sensorimotor integration, receive sensory and motor information from distinct input streams and are functionally clustered into modules reflecting the larval zebrafish's behavioral repertoire.
    1. Neuroscience
    2. Physics of Living Systems

    Gigapixel imaging with a novel multi-camera array microscope

    Eric E Thomson, Mark Harfouche ... Eva A Naumann
    A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.
    1. Neuroscience

    Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease

    Isabelle Arnoux, Michael Willam ... Albrecht Stroh
    In a premanifest mouse model of Huntington's disease at a stage very far from disease onset, significant network and behavior dysregulation was found, being rebalanced by treatment with metformin.
    1. Genetics and Genomics
    2. Neuroscience

    Cell non-autonomous regulation of health and longevity

    Hillary A Miller, Elizabeth S Dean ... Scott F Leiser
    Modulation of the aging process through cell signaling represents a recent and exciting area of study with the potential for development of therapeutics to extend human health.
    1. Neuroscience

    Magnetic eye tracking in mice

    Hannah L Payne, Jennifer L Raymond
    An accurate, robust, and lightweight technique for measuring eye movements in mice was developed using magnetic sensing, yielding the first high resolution recordings of eye movements in freely moving mice.
    1. Evolutionary Biology

    The evolution of olfactory sensitivity, preferences, and behavioral responses in Mexican cavefish is influenced by fish personality

    Maryline Blin, Louis Valay ... Sylvie Rétaux
    Individual olfactory-driven behaviors, odor preferences, and olfactory sensitivity have rapidly evolved in blind Mexican cavefish, as a quantitative genetic trait.

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