163 results found
    1. Neuroscience

    Septal cholinergic input to CA2 hippocampal region controls social novelty discrimination via nicotinic receptor-mediated disinhibition

    Domenico Pimpinella, Valentina Mastrorilli ... Marilena Griguoli
    Acetylcholine, released from cholinergic fibers originating from the medial septum, shapes social memory, and controls the CA2 hippocampal circuit via nicotinic receptors localized on GABAergic interneurons.
    1. Neuroscience

    Different types of theta rhythmicity are induced by social and fearful stimuli in a network associated with social memory

    Alex Tendler, Shlomo Wagner
    Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.
    1. Neuroscience

    Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

    Hala Harony-Nicolas, Maya Kay ... Joseph D Buxbaum
    The production, validation and study of a novel rat model for Phelan McDermid Syndrome shows an ameliorative effect of oxytocin on both social and attentional deficits.
    1. Neuroscience

    Adult-born granule cells modulate CA2 network activity during retrieval of developmental memories of the mother

    Blake J Laham, Isha R Gore ... Elizabeth Gould
    Adult-born granule cell projections are necessary for CA2 network activity and retrieval of developmental social memories.
    1. Cell Biology
    2. Neuroscience

    Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory

    Naoki Yamawaki, Hande Login ... Asami Tanimura
    Unveiling the circuit organization and functional roles of endopiriform neurons projecting to the ventral CA1.
    1. Ecology
    2. Neuroscience

    Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

    Diogo Ribeiro, Ana Rita Nunes ... Rui F Oliveira
    Individual social behavior results from the interaction between the individuals own oxytocin receptor genotype and the oxytocin receptor genotypes of other individuals present in its social environment.
    1. Medicine

    Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome

    Alba Navarro-Romero, Lorena Galera-López ... Andres Ozaita
    A mouse model of Williams–Beuren syndrome allowed us to assess the endocannabinoid system and the impact of targeting the monoacyl glycerol lipase in modulating key phenotypes such as cognitive and hypersocial phenotype as well as the cardiac phenotype.
    1. Neuroscience

    Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms

    Kyungdeok Kim, Wangyong Shin ... Eunjoon Kim
    Presynaptic adhesion molecule PTPσ in the hippocampus regulates postsynaptic NMDA receptor function and behavioral novelty recognition through mechanisms independent of their trans-synaptic binding partners.
    1. Developmental Biology
    2. Neuroscience

    The olfactory critical period is determined by activity-dependent Sema7A/PlxnC1 signaling within glomeruli

    Nobuko Inoue, Hirofumi Nishizumi ... Hitoshi Sakano
    The critical period in the mouse olfactory system is defined by activity-dependent synapse formation induced by Semaphorin7A/PlexinC1 signaling in the neonatal glomeruli.
    1. Neuroscience

    When abstract becomes concrete, naturalistic encoding of concepts in the brain

    Viktor Nikolaus Kewenig, Gabriella Vigliocco, Jeremy I Skipper
    A novel deep-learning-based computational method using object recognition to quantify visual context in naturalistic, multimodal stimuli demonstrates that a concept's perceived abstractness or concreteness dynamically depends on its visual context.

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