Acetylcholine, released from cholinergic fibers originating from the medial septum, shapes social memory, and controls the CA2 hippocampal circuit via nicotinic receptors localized on GABAergic interneurons.
Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.
Hala Harony-Nicolas, Maya Kay ... Joseph D Buxbaum
The production, validation and study of a novel rat model for Phelan McDermid Syndrome shows an ameliorative effect of oxytocin on both social and attentional deficits.
Individual social behavior results from the interaction between the individuals own oxytocin receptor genotype and the oxytocin receptor genotypes of other individuals present in its social environment.
Alba Navarro-Romero, Lorena Galera-López ... Andres Ozaita
A mouse model of Williams–Beuren syndrome allowed us to assess the endocannabinoid system and the impact of targeting the monoacyl glycerol lipase in modulating key phenotypes such as cognitive and hypersocial phenotype as well as the cardiac phenotype.
Presynaptic adhesion molecule PTPσ in the hippocampus regulates postsynaptic NMDA receptor function and behavioral novelty recognition through mechanisms independent of their trans-synaptic binding partners.
The critical period in the mouse olfactory system is defined by activity-dependent synapse formation induced by Semaphorin7A/PlexinC1 signaling in the neonatal glomeruli.
Viktor Nikolaus Kewenig, Gabriella Vigliocco, Jeremy I Skipper
A novel deep-learning-based computational method using object recognition to quantify visual context in naturalistic, multimodal stimuli demonstrates that a concept's perceived abstractness or concreteness dynamically depends on its visual context.