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38 results found
    1. Neuroscience

    A spinoparabrachial circuit defined by Tacr1 expression drives pain

    Arnab Barik et al.
    A circuit involving Tacr1-expressing neurons in the spinal cord and the parabrachial nucleus controls how mice respond to a wide range of persistently painful stimuli.
    1. Cell Biology
    2. Neuroscience

    Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans

    Jamie L Courtland et al.
    Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.
    1. Neuroscience

    Neural encoding of actual and imagined touch within human posterior parietal cortex

    Srinivas Chivukula et al.
    Single neurons in human posterior parietal cortex encode actual and imagined touch within a shared neural substrate.
    1. Neuroscience

    A rapid whisker-based decision underlying skilled locomotion in mice

    Richard A Warren et al.
    A rapid whisker-based decision underlies skilled locomotion in mice largely independent of cerebral cortex.
    1. Neuroscience

    Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD

    Da Hee Jung et al.
    High-definition anodal transcranial stimulation alleviated cognitive deficits, affected dopaminergic neurotransmission factors, increased expression of several neurotrophic factors involving brain-derived neurotrophic factor (BDNF), and activated hippocampal neurogenesis.
    1. Neuroscience

    Dynamics of gaze control during prey capture in freely moving mice

    Angie M Michaiel et al.
    During natural visual behavior in mice, orienting towards a target is driven by head movements, during which the eyes stabilize and shift the visual input.
    1. Neuroscience

    A machine-vision approach for automated pain measurement at millisecond timescales

    Jessica M Jones et al.
    Development of a fully automated pain scale using machine learning tools in computational neuroethology and creation of new software, reveals a robust circuit-dissection compatible platform for objective pain measurement.
    1. Neuroscience

    Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas

    Julia U Henschke, Janelle MP Pakan
    Anatomical projections from sensory, motor, and association cortex to the cerebellum are precisely mapped, including cortical-precerebellar connections and terminal organization, providing insight into how the cerebellum may utilize cortical information.
    1. Neuroscience

    Early life adversity decreases pre-adolescent fear expression by accelerating amygdala PV cell development

    Gabriela Manzano Nieves et al.
    Early life adversity (ELA) accelerated PV+ interneuron development in BLA and delayed the ability of pre-adolescent mice to express, but not form, an auditory conditioned fear memory in childhood.
    1. Neuroscience

    Keratinocytes contribute to normal cold and heat sensation

    Katelyn E Sadler et al.
    Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.

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