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    1. Developmental Biology

    Induction of human somatostatin and parvalbumin neurons by expressing a single transcription factor LIM homeobox 6

    Fang Yuan, Xin Chen ... Yan Liu
    Inducing expression of a single transcription factor LIM homeobox 6 showed efficient generation of human parvalbumin and somatostatin interneurons.
    1. Cell Biology

    A δ-cell subpopulation with a pro-β-cell identity contributes to efficient age-independent recovery in a zebrafish model of diabetes

    Claudio Andrés Carril Pardo, Laura Massoz ... Isabelle Manfroid
    Most regenerated cells after β-cell damage in zebrafish are Insulin+ Somatostatin+ bihormonal cells that are functional and able to restore glucose control.
    1. Neuroscience

    Somatostatin-expressing parafacial neurons are CO2/H+ sensitive and regulate baseline breathing

    Colin M Cleary, Brenda M Milla ... Daniel K Mulkey
    Cellular and chemogenetic approaches identify a novel mode of chemotransduction involving regulation of basal breathing by CO2/H+-dependent disinhibition.
    1. Neuroscience

    Cellular mechanisms underlying central sensitization in a mouse model of chronic muscle pain

    Yu-Ling Lin, Zhu-Sen Yang ... Cheng-Chang Lien
    Maladaptive changes of pro-nociceptive neurons in the central nucleus of the amygdala drive the chronification of muscle pain and comorbid affective behaviors.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on somatostatin- and parvalbumin-expressing cortical GABAergic neurons

    Amy N Shore, Keyong Li ... Matthew C Weston
    An epilepsy-associated potassium channel variant causes neuron-type-dependent alterations in ionic currents, neuronal excitability, and network connectivity.
    1. Neuroscience

    An inhibitory corticostriatal pathway

    Crystal Rock, Hector Zurita ... Alfonso junior Apicella
    The discovery of somatostatin-positive inhibitory neurons projecting from mouse cortex to striatum shows that corticostriatal pathways are not exclusively excitatory.
    1. Genetics and Genomics
    2. Neuroscience

    A scalable platform for the development of cell-type-specific viral drivers

    Sinisa Hrvatin, Christopher P Tzeng ... Michael E Greenberg
    Highly paralleled functional evaluation of enhancer activity in single cells generates new cell-type-specific tools with broad medical and scientific applications.
    1. Neuroscience

    Cell type-specific long-range connections of basal forebrain circuit

    Johnny Phong Do, Min Xu ... Yang Dan
    Whole-brain mapping of the basal forebrain circuits reveals a connection diagram with highly convergent inputs and divergent outputs.
    1. Neuroscience

    Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex

    Wuqiang Guan, Jun-Wei Cao ... Yong-Chun Yu
    Our work demonstrated that eye opening differentially modulates inhibitory synaptic transmission from Sst-INs and FS-INs to excitatory neurons in the mammalian cortex.
    1. Neuroscience

    Altered hippocampal interneuron activity precedes ictal onset

    Mitra L Miri, Martin Vinck ... Jessica A Cardin
    GABAergic interneuron populations in the hippocampus exhibit cell-type-specific patterns of disruption in advance of seizure onset.
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