A rare population of endothelial cells emerges from a bipotent muscle progenitor population in the paraxial mesoderm and provides niche support to induce hematopoietic stem cells.

Interplay between FGF-induced bHLH transcription factors and BMP-induced bHLH inhibitory id genes govern mesodermal cell fate choice along the mediolateral axis in both zebrafish and mouse.

Retinoic acid-dependent somite morphogenesis induces notochord-endoderm separation required for midline angioblast migration and axial blood vessel development.

Zebrafish mutants and human endothelial cell experiments reveal that GIPC family endocytic adaptors bind to the Semaphorin receptor PLEXIND1, a critical regulator of vascular development, to negatively modulate its signaling.

Live imaging coupled with cell lineage tracing in chick and mouse embryos reveal that the cardiac regulatory gene Nkx2.5 is also transiently expressed in early extra-cardiac hemogenic angioblasts that migrate to the heart, yolk sac and dorsal aorta.

Visualization and quantitative analyses of calcium ion oscillations in the endothelial cells of zebrafish embryos reveal how vascular endothelial growth factor (VEGF) and Dll4/Notch signaling regulate sprouting angiogenesis.

Angiopoietin-like proteins signal through notch via receptor interaction and can regulate Notch cleavage/activation.

A new role for nephronectin and integrin α8 signaling during neural crest cell migration in the developing cornea has been identified.

The transcription factor GATA6 selects the embryonic vessels that will be reorganized into the major thoracic arteries by promoting local differentiation of vascular smooth muscle cells.