Emma S Sherling, Ellen Knuepfer ... Christiaan van Ooij
The rhoptry protein RhopH3 is crucial for the invasion and growth of the malaria parasite and disruption of it provides insight into the binding of the parasite to the host red blood cell and into the formation of new import pathways.
Microfluidic methods are used to quantitatively probe single yeast cells' response to either simultaneous or sequential stresses, revealing the dynamic interplay between two antagonistic inputs, osmotic stress and glucose starvation.
A hyperpolarization-activated cation channel, counteracting membrane depolarization, delimits the excitability of receptor neurons subjected to naturally prolonged stimulation to preserve the function of neighboring receptor neurons in Drosophila gustation.
Rafael Renteria, Christian Cazares ... Christina M Gremel
Chronic alcohol exposure results in a long-lasting, enhanced endocannabinoid signalling at orbitostriatal synapses that is expressed in a projection-, synapse-, and behaviorally computation-specific manner.
Fruit flies have special neurons in their pharynx with ionotropic receptors to prevent consuming too much salt, which was confirmed using a variety of behavioral and physiological assays.