Softer sound appears closer to midline than louder sound, conflicting with a labelled-line representation of auditory space and supporting the idea that humans use rate coding when calculating sound directionality.
Training enables adult humans to rapidly adapt their sound localization abilities to unilateral hearing loss by combining different strategies that rely on partially distinct neurophysiological substrates.
The location of impact sounds, common stimuli whose detection is crucial for survival, is encoded by a precise interaction between excitation and inhibition rather than coincidence detection of excitatory events.
Sox2 transcription is not correlated with spatial proximity of its essential regulatory enhancer in embryonic stem cells, suggesting gene transcription is not limited to periods of direct enhancer-promoter contact.
Human genomic DNA contains uracil in the late replicating, constitutive heterochromatic regions, while treatment with drugs perturbing thymidylate biosynthesis shifts the uracil distribution pattern towards the euchromatin in UNG-inhibited cells.