2,451 results found
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Dilation of fusion pores by crowding of SNARE proteins

    Zhenyong Wu et al.
    A few SNARE complexes suffice to fuse membranes, but many more are needed to dilate the nascent fusion pore by molecular crowding for efficient neurotransmitter or hormone release during exocytosis.
    1. Computational and Systems Biology
    2. Neuroscience

    Contrast sensitivity reveals an oculomotor strategy for temporally encoding space

    Antonino Casile et al.
    Fixational eye movements transform the spatial scene into temporal modulations on the retina, which, together with the known sensitivities of retinal neurons, provide a comprehensive account of human spatial sensitivity.
    1. Developmental Biology
    2. Neuroscience

    Presynaptic developmental plasticity allows robust sparse wiring of the Drosophila mushroom body

    Najia A Elkahlah et al.
    Sensory innervation density in the insect associative learning center is set by postsynaptic cells and accomplished by flexible allocation of processes by presynaptic cells.
    1. Neuroscience

    Large-scale two-photon imaging revealed super-sparse population codes in the V1 superficial layer of awake monkeys

    Shiming Tang et al.
    Two-photon imaging reveals super-sparse responses to natural images in primate V1, which carry sufficient information for discrimination of the input natural images with high accuracy.
    1. Neuroscience

    Task-dependent recurrent dynamics in visual cortex

    Satohiro Tajima et al.
    A decoding-based, state-space reconstruction reveals that neurons in macaque IT cortex change the structure of their collective attractor dynamics depending on task contexts.
    1. Neuroscience

    Learning multiple variable-speed sequences in striatum via cortical tutoring

    James M Murray, G Sean Escola
    Inspired by the sparse, sequential neural activity patterns observed in striatum, a new circuit model implements variable-speed activity, the encoding of multiple sequences, and a tutor/student relationship between cortex and striatum.
    1. Neuroscience

    Silent synapses generate sparse and orthogonal action potential firing in adult-born hippocampal granule cells

    Liyi Li et al.
    Young neurons of the adult hippocampus are synaptically activated by a small group of non-overlapping afferent excitatory fibers, due to high synaptic gain and sparse connectivity, important for sparse and orthogonal coding during hippocampal information processing.
    1. Microbiology and Infectious Disease

    Transcriptomics: Revisiting the genomes of herpesviruses

    Bhupesh K Prusty, Adam W Whisnant
    Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
    Insight
    Available as:
    • HTML
    • PDF
    1. Computational and Systems Biology

    Science Forum: Wikidata as a knowledge graph for the life sciences

    Andra Waagmeester et al.
    Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.

Refine your results by:

Type
Research categories