175 results found
    1. Epidemiology and Global Health

    Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults

    Flavia Camponovo et al.
    Malaria pre-exposed volunteers exhibit large breadth of humoral immune responses, with strong variation between individuals, which might compromise vaccine-induced humoral immune response due to natural imprinting.
    1. Epidemiology and Global Health

    The effect of climate change on yellow fever disease burden in Africa

    Katy AM Gaythorpe et al.
    Analysis of yellow fever burden in Africa illustrates the need to consider the effect of a changing climactic conditions when planning future intervention strategies.
    1. Epidemiology and Global Health

    Risk of psychiatric disorders among the surviving twins after a co-twin loss

    Huan Song et al.
    A population-based analysis demonstrates that surviving twins who lose their co-twins by death are at considerably elevated risks of developing psychiatric disorders.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Isolation and transcriptomic analysis of Anopheles gambiae oenocytes enables the delineation of hydrocarbon biosynthesis

    Linda Grigoraki et al.
    Delineation of the cuticular hydrocarbon biosynthetic pathway in malaria vectors is a key step in understanding how mosquitoes adapt to anthropogenic change and vector control interventions.
    1. Epidemiology and Global Health

    Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study

    Wilson Suraweera et al.
    Prevention and antivenom treatment could reduce snakebite deaths, which killed 1.2 million Indians from 2000-2019, about 70% of which occurred in eight states, and half during four rainy months.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants

    Allison L Hicks et al.
    Sampling informed by pathogen genomic data may facilitate more efficient detection of novel antibiotic resistance than random sampling.
    1. Computational and Systems Biology
    2. Neuroscience

    Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions

    Amin Haghani et al.
    Transcriptome analysis of mouse brain revealed that the APOE4 allele and sex can alter air pollution neurotoxicity in adults.
    1. Epidemiology and Global Health
    2. Immunology and Inflammation

    Science Forum: A Global lmmunological Observatory to meet a time of pandemics

    Michael J Mina et al.
    The COVID-19 pandemic has clearly demonstrated the need for a global system to monitor the dynamics of susceptibility and immunity, as well as infection, during epidemics and pandemics.
    1. Epidemiology and Global Health

    Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

    Daniel W Belsky et al.
    Methylation pace of aging is a novel measure requiring only a blood sample that clinical-trial and observational studies can use to test if treatments modify how fast participants are aging.
    1. Epidemiology and Global Health

    Estimates of the global burden of Japanese encephalitis and the impact of vaccination from 2000-2015

    Tran Minh Quan et al.
    Modelling analysis reveals the burden of Japanese Encephalitis is greater than previously thought, and although vaccination has reduced burden, there are remaining places with a great need for vaccination.

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