The phosphorylation of FLS2 may activate flg22-triggered immunity by facilitating the partitioning of FLS2 into functional AtRem1.3-associated nanodomains.
Flow hemodynamic activation of endothelial klf2a is a mechanism regulating initial vascular smooth muscle cell differentiation on circle of Willis arteries.
Burst activity can be described in all three signal domains and sensorimotor beta burst activity propagates along two axes either parallel or perpendicular to the central sulcus.
Extended biochemical and functional analyses in primary neurons show that early neuronal morphogenesis critically relies on cooperation of the actin nucleator Cobl and its ancestor Cobl-like and uncover their cooperative mechanisms at dendritic branch initiation sites.
During zebrafish embryogenesis, dact1 and dact2 are necessary for axis lengthening and craniofacial morphogenesis, and the protease capn8 is misexpressed in dact1/2 mutants.
Tucked within a well-known story of diverging gene function is a single enhancer encoding two inseparable specificities that regulates two adjacent genes, each with different spatiotemporal expression patterns.
Genetic analyses combining photoconvertible cell signalling reporters with gain- and loss-of function manipulations reveal a novel role for Notch signalling in controlling Hedgehog response in neural progenitor cells.
Analysis of insulin secretion patterns in pancreatic islets shows that microtubules control β-cell heterogeneity by regulating initiation and timing of secretion hot spot activity in parallel with Ca2+ signaling.
Gemma LM Fisher, Jani R Bolla ... David J Sherratt
Topoisomerase IV and the ter-binding protein MatP competitively bind the hinge domain of the Escherichia coli Structural Maintenance of Chromosomes complex, MukB, leading to spatiotemporal regulation of MukBEF-topoisomerase IV activity.
A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.
