1,036 results found
    1. Ecology
    2. Evolutionary Biology
    The Natural History of Model Organisms

    The Natural History of Model Organisms

    Edited by Ian Baldwin et al.
    Essays on the wild lives of model organisms, from Arabidopsis to the zebrafish.
  1. eLife latest: Introducing Scientific Correspondence at eLife

    A new article type allows scientists to challenge the results reported in eLife papers, and gives the original authors an opportunity to respond.
  2. Life story: Chileshe Mabula-Bwalya

    Adjusting to a new identity as a mother comes with challenges, but with help, a rewarding research career is possible.
  3. Annual report: Looking back on 2017

    A reflection on eLife's achievements in 2017, notably in convening and supporting communities, modernising technology for research communication and partnering with early-career researchers.
    1. Neuroscience

    Spatial readout of visual looming in the central brain of Drosophila

    Mai M Morimoto et al.
    In the Drosophila central brain, synaptic connectivity extracts visual-spatial information from the axons of looming sensitive LC6 neurons that terminate in a glomerulus with minimal retinotopy.
    1. Developmental Biology

    Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models

    Kyeong-Hye Moon et al.
    Developmental defects of the cochlea caused by dysregulation of sonic hedgehog signaling are the potential etiology for hearing loss in a group of ciliopathies with defective ciliogenesis.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Genome streamlining in a minute herbivore that manipulates its host plant

    Robert Greenhalgh et al.
    The genome of a tiny tomato pest reveals mechanisms that underlie metazoan genome reduction.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

    Julien G Roth et al.
    A model of in vitro human corticogenesis identifies alterations in gene expression caused by loss of 16p11.2 CNV genes in hiPSC-derived progenitor cells.
    1. Cell Biology

    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast

    Nathaniel L Hepowit et al.
    Ser57 phosphorylation of ubiquitin protects the cell during proteotoxic stress.
    1. Cell Biology

    Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

    Hiromi Imamura et al.
    Cleavage of pannexin-1 channel by caspases facilitates the loss of intracellular ATP level and attenuates glycolytic metabolism of apoptotic cells.

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