3,445 results found
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase, and a cytosine base editor

    Nicole Herrmann May, Ngoc Anh Cao ... Tom Beneke
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Ecology
    2. Evolutionary Biology

    Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene

    Vendula Šlechtová, Tomáš Dvořák ... Jörg Bohlen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Mistargeted retinal axons induce a synaptically independent subcircuit in the visual thalamus of albino mice

    Sean McCracken, Liam McCoy ... Josh Morgan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)

    Mathew D Edwards, Ziwei Yin ... Yoh Isogai
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

    Prateeka Borar, Tapan Biswas ... Smarajit Polley
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Neuroscience

    Diverse prey capture strategies in teleost larvae

    Duncan S Mearns, Sydney A Hunt ... Herwig Baier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease

    Trevor Fisher, Mehaben Patel ... Helene Baribault
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Microbiology and Infectious Disease

    Frequent intertrophic transmission of Wolbachia by parasitism but not predation

    Zhi-Chao Yan, Lan-Da Qi ... Yuan-Xi Li
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody

    Joar Esteban Pinto Torres, Mathieu Claes ... Yann G.-J Sterckx
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation

    James B Isbister, András Ecker ... Michael W Reimann
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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