7,261 results found
    1. Neuroscience

    Heritability and cross-species comparisons of human cortical functional organization asymmetry

    Bin Wan, Şeyma Bayrak ... Sofie L Valk
    Human brain suggests an asymmetric organization along a functional cortical axis describing a hierarchical functional trajectory from perceptual/action to abstract cognition, which is heritable and comparable with macaque brain, suggesting (phylo)genetic conservation and adaptation.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species

    Natalia Petrenko, Kevin Struhl
    Although the preinitiation complex for transcriptional initiation by RNA polymerase II contains highly conserved general transcription factors, there are kinetic and compositional differences in the initiation process among eukaryotic species.
    1. Ecology
    2. Evolutionary Biology

    Sex-specific effects of cooperative breeding and colonial nesting on prosociality in corvids

    Lisa Horn, Thomas Bugnyar ... Jorg JM Massen
    A systematic experimental comparison of prosocial behavior in eight corvid species reveals sex-specific effects of cooperative breeding and colonial nesting, thereby adding important new insights regarding the evolution of prosociality.
    1. Neuroscience

    Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

    Vasiliki-Ilya Gargareta, Josefine Reuschenbach ... Hauke B Werner
    Comparing humans and mice, the protein composition of central nervous system myelin and the transcriptional profiles of myelin-producing oligodendrocytes are largely similar with respect to abundant structural myelin constituents but show divergent expression of a range of other distinct genes.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

    Rémi Allio, Marie-Ka Tilak ... Frédéric Delsuc
    High-quality genomes can be obtained from roadkill samples and used in population genomics for species delimitation with conservation implications.
    1. Cell Biology

    Direct comparison of clathrin-mediated endocytosis in budding and fission yeast reveals conserved and evolvable features

    Yidi Sun, Johannes Schöneberg ... David G Drubin
    Quantitative comparison of clathrin-mediated endocytosis in budding and fission yeast identified conserved mechanisms and species-specific adaptations with broad implications that extend from yeast to humans.
    1. Computational and Systems Biology

    Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse

    Zeyneb Kurt, Jenny Cheng ... Xia Yang
    Cross-species multiomics network modeling revealed tissue-specific regulatory genes, pathways, and networks shared between mouse and human or unique to each species for atherosclerosis and coronary artery disease.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Circular RNA repertoires are associated with evolutionarily young transposable elements

    Franziska Gruhl, Peggy Janich ... David Gatfield
    Evolutionary analyses suggest that most mammalian circRNAs did not emerge from common ancestral circRNA precursors, arguing against widespread functional conservation.
    1. Neuroscience

    Single-cell and single-nucleus RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates, and humans

    Trygve E Bakken, Cindy TJ van Velthoven ... Bosiljka Tasic
    Transcriptomic differences between relay neurons in the mature mammalian dLGN are subtle relative to striking differences in morphology and cortical projection targets.
    1. Developmental Biology
    2. Neuroscience

    Regulation of nerve growth and patterning by cell surface protein disulphide isomerase

    Geoffrey MW Cook, Catia Sousa ... Roger J Keynes
    The nerve growth-repellent activity that generates spinal nerve repeat-patterning in birds and mammals is identified at the molecular level, and a similar system is revealed in adult brain grey matter.

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