The emergent organization of bacterial proteomes—the integration of proteins into collective networks that encode function—can be defined purely from spectral analysis of ortholog covariation across extant diversity.

Two different analysis approaches for measuring neural synchronization to natural music revealed strongest synchronization to musical spectral flux as opposed to the more commonly used amplitude envelope.

A community-based international effort generates standardized HLA allele-specific peptide assay libraries and enables the analysis of the human immunopeptidome by SWATH mass spectrometry.

Visual narrow-band gamma rhythms are reduced in mild cognitive impairment and Alzheimer’s disease, confirming previous rodent research and forming crucial first steps for development of EEG-based biomarkers for humans.

Anatomical tracing and physiological recordings reveal neuronal pathways through which the cerebellum may influence hippocampal activity.

Fluorescence fluctuation spectroscopy is implemented for detection of up to four molecular species, allowing users to quantify molecular interactions and stoichiometry of multicomponent complexes in live cells, in a wide range of biological processes, from membrane signaling to viral assembly.

Non-oscillatory brain activity can be used to monitor arousal levels during both NREM and REM sleep as well as under general anesthesia with propofol.

Auto-inhibition of ISWI-family ATP-dependent chromatin remodelers is relieved by a conserved feature of the nucleosome.

Invasive electrophysiological recording measures neuronal transmembrane current timescales across human cortex, which lengthens from sensory to association regions, follows variations in ion channel expressions, and alters with behavior and aging.

Asymmetries between the shape of the left and right human cortex are highly unique to individuals, akin to a neuroanatomical fingerprint, related to cognitive function, and primarily driven by person-specific environmental influences.