Targeted SOCS3 null mice reveal that maturation of cortical bone comprises both pore closure and accumulation of high density bone, requiring local suppression of gp130-STAT3 in osteocytes and subsequent osteoclastogenesis.
New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
Increased mass enhances speed but compromises turning capacity in pursuit predators; this has widespread ramifications for the best strategies for predators and prey during chases according to their relative masses.
The principle underlying the appearance of the growth plate, an organ responsible for longitudinal growth, has implications for various cartilage pathologies including growth abnormalities in children, trauma and osteoarthritis.
Undulatory animals moving on the surface must manage material memory by either having a slender anatomy that facilitates avoiding previously remodeled substrate, or using waveshapes that effectively utilize the memory.