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    1. Neuroscience

    An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction

    Steven R Sando, Nikhil Bhatla ... H Robert Horvitz
    By driving the localized contraction of subcellular muscle regions, a single motor neuron reverses the flow of material in the Caenorhabditis elegans pharynx, a neuromuscular pump, converting feeding into spitting.