Nicolas Michalski, Juan D Goutman ... Christine Petit
Targeted mutations in a Ca2+-binding site of otoferlin, a transmembrane protein of synaptic vesicles defective in a recessive form of deafness, reveal its Ca2+ sensor role both for vesicle fusion and vesicle pool replenishment.
SUSD4 loss-of-function induces misregulation of GLUA2 degradation and of synaptic plasticity suggesting a mechanism for its potential contribution to neurodevelopmental disorders.
The auditory cortex temporarily stores task-relevant information by persistently changed neuronal activity of single neurons and of neuronal populations.
Sleep-encoded vocabulary influences awake decision-making 36 hr later, particularly when targeting the vocabulary to slow-wave troughs, which suggests that unconscious episodic memory formation during deep sleep is possible.
Theoretical analysis of the current literature reveals the structural assembly, transport regulation, and molecular functions of the BBSome, emphasizing its roles in cilium-related processes.
Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.
GLMsingle is a publicly available toolbox for analyzing fMRI time-series data that leverages data-driven optimization techniques to improve the accuracy of single-trial BOLD response estimates.
Julio D Perez, Nimrod D Rubinstein ... Catherine Dulac
A subset of genes in the mouse brain show dynamically regulated and unequal expression of maternally and paternally derived variants, with implications for brain development and function.