27 results found
    1. Developmental Biology
    2. Physics of Living Systems

    Rolling controls sperm navigation in response to the dynamic rheological properties of the environment

    Meisam Zaferani, Farhad Javi ... Alireza Abbaspourrad
    Rheological properties of the environment regulate sperm swimming and navigational behavior through suppression or reactivation of sperm rolling around its longitudinal axis.
    1. Physics of Living Systems

    Rheotaxis facilitates upstream navigation of mammalian sperm cells

    Vasily Kantsler, Jörn Dunkel ... Raymond E Goldstein
    Mammalian sperm subject to shear flow swim in upstream spirals along the walls bounding such flows, thereby demonstrating a robust mechanism for upstream navigation to the ovum.
    1. Cell Biology
    2. Developmental Biology

    Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation

    Xiaofei Bai, Jeff Bouffard ... Andy Golden
    Depletion of the mechanosensitive ion channel PEZO-1 in C. elegans disrupts the sheath and spermathecae cells to disrupt oocyte ovulation, resulting in crushed oocytes.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    A K+-selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm

    Sylvia Fechner, Luis Alvarez ... U Benjamin Kaupp
    Zebrafish sperm display an unusual pathway for Ca2+ signalling.
    1. Cell Biology
    2. Developmental Biology

    The sperm hook as a functional adaptation for migration and self-organized behavior

    Heungjin Ryu, Kibum Nam ... Jung-Hoon Park
    The interaction between the sperm hook and the female reproductive tract, including various sperm dynamics related to their movement through the reproductive tract, has been directly observed for the first time using deep tissue live imaging.
    1. Physics of Living Systems

    Sperm chemotaxis is driven by the slope of the chemoattractant concentration field

    Héctor Vicente Ramírez-Gómez, Vilma Jimenez Sabinina ... Adán Guerrero
    The slope of the chemoattractant concentration gradient is a driving force for sperm chemotaxis, by coordinating the entrainment of information flow between sensing, signaling and motility.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    The Ca2+-activated K+ current of human sperm is mediated by Slo3

    Christoph Brenker, Yu Zhou ... Timo Strünker
    The principal potassium ion channel in human sperm, Slo3, is primarily activated by calcium ions and controls the membrane potential of human sperm by intracellular calcium ion levels rather than intracellular pH.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility

    Jean-Ju Chung, Kiyoshi Miki ... David E Clapham
    A new component, CatSper zeta, is required for continuous alignment of the calcium channel along the sperm's tail and is crucial for normal sperm swimming behavior and fertility.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    High-speed, three-dimensional imaging reveals chemotactic behaviour specific to human-infective Leishmania parasites

    Rachel C Findlay, Mohamed Osman ... Laurence G Wilson
    High-speed holographic microscopy shows that Leishmania parasites modify their swimming behaviour to target human macrophages.

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