Ancient features of the p53 regulatory network are coupled to the stem cell compartment in normal and pathologic contexts.

An identical DNA base pair change has occurred in divergent sticklebacks to alter the expression of a major developmental gene controlling armor plates, thus providing a molecular link between particular enhancer changes, cell signaling, and repeated skeletal evolution in natural populations.

The stem cell orientation checkpoint senses the correct orientation of centrosomes via their interactions with a protein called Bazooka.

GnT1IP-L is a membrane bound glycoprotein that interacts with MGAT1 in the Golgi, but not in the endoplasmic reticulum, to regulate complex N-glycan synthesis.

A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.

C. elegans germline stem cells become quiescent under starved conditions, and this quiescence maintains the stem cell state even in the absence of GLP-1/Notch signaling, which is otherwise essential for stem cell maintenance.

Zebrafish sperm display an unusual pathway for Ca²⁺ signalling.

The vertebrate testis-determining gene, Sox9, also controls adult testis maintenance in mammals, acting redundantly with its paralog Sox8.

Rescue of DUX4-induced muscle pathology by the RET inhibitor Sunitinib reveals the therapeutic potential for treatment of Facioscapulohumeral muscular dystrophy using tyrosine kinase inhibitors.

A small brain-derived lipid prevents bristle worms from entering maturation and death, challenging current views of hormone evolution and pesticide specificity.