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Disruption of quality control pathways that function at distinct steps to mitigate errors in translation evoke similar cellular responses and pathologies.

Rescue of DUX4-induced muscle pathology by the RET inhibitor Sunitinib reveals the therapeutic potential for treatment of Facioscapulohumeral muscular dystrophy using tyrosine kinase inhibitors.

Study of human, knockout mice, and in-vitro models revealed CEP78 absence is the genetical cause of cone-rod dystrophy and male infertility with multiple morphological abnormalities of sperm flagella, CEP78 interacted with IFT20 and TTC21A to modulate cilliogenesis and centriole length.

Axonemal dynein light intermediate polypeptide 1 is required for sperm formation and male fertility through association with MEIG1/PACRG complex in the manchette, involvement in a cargo transport system, intraflagellar transport, and sperm individualization.

PCGF6 links sequence specific target recognition by the MAX/MGA transcription factor complex to PRC1 (polycomb repressive complex 1) -dependent transcriptional silencing of germ cell-specific genes in mouse pluripotent stem cells.

Cylicin-1, a perinuclear theca protein, is critical for acrosome attachment and sperm head morphology.

Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.

In Caenorhabditis elegans histone methylation (H3K9me3) controls the synthesis of heritable small RNAs in a gene-specific manner and thus enables 'flagging' of newly-acquired genes.

Identification and functional characterization of the first non-chordate kisspeptin neuropeptide system in the sea cucumber indicates the ancient origin of the intracellular signaling and physiological functions of this molecular system.