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    1. Neuroscience

    Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila

    Martina Held, Rituja S Bisen ... Jan M Ache
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Decoding the physics of observed actions in the human brain

    Moritz F Wurm, Doruk Yiğit Erigüç
    Inferior parietal and lateral occipitotemporal cortex encode the effects of actions at an abstract level of representation, independently of the body movements that induce them.
    1. Structural Biology and Molecular Biophysics

    Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from coarse-grained and atomistic simulations

    Sneha Dixit, Frank Noé, Thomas R Weikl
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

    Parveen Goyal, KanagaVijayan Dhanabalan ... Subramanian Ramaswamy
    The first structure of a Neu5Ac bound Tripartite ATP-independent Periplasmic transporter (TRAP) reveals the presence of three ion binding sites.
    1. Computational and Systems Biology

    A model-based factorization method for scRNA data unveils bifurcating transcriptional modules underlying cell fate determination

    Jun Ren, Ying Zhou ... Qiyuan Li
    A novel method for factorizing complex cellular trajectories into interpretable bifurcation processes enhances the understanding of cell fate determination through the identification of key biological determinants in scRNA-seq data.
    1. Cell Biology

    DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli

    Alexandros Papagiannakis, Qiwei Yu ... Christine Jacobs-Wagner
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Evolutionary Biology

    Variations and predictability of epistasis on an intragenic fitness landscape

    Sarvesh Baheti, Namratha Raj, Supreet Saini
    Not revised
    Reviewed Preprint v1
    • Important
    • Inadequate
    1. Neuroscience

    Sensitivity to visual features in inattentional blindness

    Makaela Nartker, Chaz Firestone ... Ian Phillips
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

    Taro Ichimura, Taishi Kakizuka ... Takeharu Nagai
    Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm2 has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.
    1. Neuroscience

    An emerging view of neural geometry in motor cortex supports high-performance decoding

    Sean M Perkins, Elom A Amematsro ... Mark M Churchland
    Neural activity in motor cortex displays unexpected properties, making it possible to accurately decode behavior using a straightforward and interpretable approach.
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