673 results found
    1. Neuroscience

    Mapping cortical mesoscopic networks of single spiking cortical or sub-cortical neurons

    Dongsheng Xiao et al.
    Mesoscale cortical calcium activity correlating with single cortical and thalamic cell spiking reveal rich dynamics and support a novel approach for investigating in vivo functional networks in the mammalian brain.
    1. Computational and Systems Biology
    2. Neuroscience

    Fast and flexible sequence induction in spiking neural networks via rapid excitability changes

    Rich Pang, Adrienne L Fairhall
    Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
    1. Neuroscience

    Dendritic sodium spikes are required for long-term potentiation at distal synapses on hippocampal pyramidal neurons

    Yujin Kim et al.
    At distal synapses onto hippocampal CA1 pyramidal neurons, synaptic plasticity is dependent on dendritically initiated sodium spikes, thus establishing a new role for voltage-gated sodium channels in the dendrites that may have important implications for how learning rules are implemented.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A self-balancing circuit centered on MoOsm1 kinase governs adaptive responses to host-derived ROS in Magnaporthe oryzae

    Xinyu Liu et al.
    A phosphorylation circuitry balancing among kinase, transcription factor, transcription repressor, and phosphatase in response against host immunity during M. oryzae–rice interaction.
    1. Neuroscience

    Apical length governs computational diversity of layer 5 pyramidal neurons

    Alessandro R Galloni et al.
    Layer 5 pyramidal neurons vary substantially in dendritic excitability between primary and secondary visual cortex, likely due to a counterintuitive amplifying effect of long apical dendrites.
    1. Neuroscience

    Revealing the distribution of transmembrane currents along the dendritic tree of a neuron from extracellular recordings

    Dorottya Cserpán et al.
    A computational method reveals current sources along the dendritic tree of a single neuron of known morphology from extracellular potential.
    1. Computational and Systems Biology
    2. Neuroscience

    Mapping nonlinear receptive field structure in primate retina at single cone resolution

    Jeremy Freeman et al.
    Multi-electrode recordings and modeling are combined to reveal the transformations of signals from cones to bipolar cells and then to ganglion cells within the primate retina.
    1. Neuroscience

    Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex

    Holger Dannenberg et al.
    Spatial accuracy of grid cell firing correlates with the slope of the local field potential theta frequency vs. running speed relationship and integrates velocity signals over past time.
    1. Neuroscience

    Temporal transitions of spontaneous brain activity

    Zhiwei Ma, Nanyin Zhang
    Analysis of resting-state fMRI data revealed nonrandom temporal transitions between spontaneous brain activity patterns in both awake rats and humans.
    1. Neuroscience

    M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease

    Sara Fernández-García et al.
    M2 cortex-dorsolateral striatum circuit is functionally altered in Huntington's disease and, by boosting its activity, we reverse symptoms at behavioral, physiological, and morphological level in symptomatic mice.

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