A genetically-defined population of spinal interneurons is reciprocally connected with spinal locomotor circuits and mediates recovery of locomotor function following spinal cord transection.

Spinal dI2 interneurons relay peripheral and intraspinal feedback to premotor networks in the spinal cord and the cerebellum to ensure the stability of bipedal stepping.

Single-cell transcriptomics of larval zebrafish spinal cord reveal ion channels and exocytotic machinery that enhance transmitter release in neuronal types shown to mediate high-speed swimming and escape behavior.

The miR-34/449 family is abundantly expressed in the central nervous system, and fine-tunes optimal numbers of spinal interneurons to ensure sensory-motor circuit outputs.

Retrograde transport of NT-3 stimulated the reorganization of lumbar neural circuitry and synaptic connectivity remote to a thoracic SCI, along with improved behavioral recovery.

Newly developed methods to genetically target cerebrospinal fluid-contacting neurons reveal unique caudorostrally extended projections and recurrent connections in the spinal motor circuitry to control locomotion in mice.

Bioluminescence monitoring and selective silencing in zebrafish larva reveal a novel sensorimotor circuit modulating speed in the moving spinal cord.

Persistent, non-random sensorimotor connectivity reveals the capacity of intrinsic spinal networks to purposefully replay and modify learned patterns of neural transmission during unconsciousness.

Two anatomically and genetically distinct subtypes of spinal V2b neurons provide inhibition onto motor circuits and serve as a brake on locomotor speed.

Multiple trans-synaptic tracing methods reveal that there is no spatial segregation between flexor and extensor premotor interneurons in the lumbar spinal cord.