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    1. Developmental Biology

    aPKC-mediated displacement and actomyosin-mediated retention polarize Miranda in Drosophila neuroblasts

    Matthew Robert Hannaford, Anne Ramat ... Jens Januschke
    The actomyosin network and phospho-regulation combine to polarize fate determinants at the Drosophila neuroblast cell cortex.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends

    Taylor A Reid, Courtney Coombes ... Melissa K Gardner
    EB1 targeting to growing microtubule plus-ends is facilitated by tapered microtubule tip structures.
    1. Cell Biology
    2. Developmental Biology

    The full length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice

    Yan Huang, Nina Bucevic ... Ignasi Roig
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Molecular, cellular, and developmental organization of the mouse vomeronasal organ at single cell resolution

    Max Henry Hills, Limei Ma ... C Ron Yu
    A transcriptomic atlas of the mouse vomeronasal organ reveals novel receptor co-expression patterns and provides a framework for understanding sensory neuron lineage and receptor specification.
    1. Computational and Systems Biology
    2. Developmental Biology

    Size control of the inner ear via hydraulic feedback

    Kishore R Mosaliganti, Ian A Swinburne ... Sean G Megason
    Size regulation of the otic vesicle, the progenitor of the inner ear, is mediated by mechanical feedback involving fluid influx, hydraulic pressure, and tissue mechanics.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Affimer proteins are versatile and renewable affinity reagents

    Christian Tiede, Robert Bedford ... Darren Charles Tomlinson
    The Affimer technology represents renewable binding reagents for molecular biology, which provides research scientists and industry with an alternative to the recently criticised use of animal-produced antibodies.
    1. Cancer Biology

    Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent

    Andrea Vallés-Martí, Franziska Böttger ... Connie R Jiménez
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Computational and Systems Biology

    Chronology of motor-mediated microtubule streaming

    Arvind Ravichandran, Özer Duman ... Gerhard Gompper
    Microtubule streaming driven by molecular motors covers characteristic times that span several orders of magnitude from fast, single-microtubule sliding on molecular scales to slow, collective motion on cellular scales.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Self-organised segregation of bacterial chromosomal origins

    Andreas Hofmann, Jarno Mäkelä ... Seán M Murray
    The self-organising condensin MukBEF positions chromosomal origins in Escherichia coli..
    1. Neuroscience

    Separating the control of moving and holding in post-stroke arm paresis

    Alkis M Hadjiosif, Kahori Kita ... John W Krakauer
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid