Expression patterns and biophysical properties of acid-sensing ion channels in numerous bilaterian animals offer insight into the deployment of ion channels by the evolving nervous system in complex animals.
B Duygu Özpolat, Mette Handberg-Thorsager ... Guillaume Balavoine
Lineage tracing at single-cell resolution reveals the presence of mesoteloblasts, the embryonic origin of mesodermal growth zone cells, and diverse cell cycling patterns of these lineages in the 'Polychaete' annelid Platynereis.
Cuttlefish embryos reveal that cephalopod mollusks evolved specialized arms and tentacles by activating the same genetic circuits that control development of limbs in arthropods and vertebrates.
Christopher E Laumer, Andreas Hejnol, Gonzalo Giribet
A phylogeny of all major groups of flatworms based on hundreds of genes sheds new light the early evolution of this important metazoan phylum, with particular significance for the original of vertebrate parasitism.
Benoit G Godard, Remi Dumollard ... Alex McDougall
Cell geometry and polarity domains act in concert to determine spindle positioning, with cell geometry modulating the effect of cortical polarity domains by influencing the position of the spindle relative to those polarity domains.
Luis V Nobre, Katie Nightingale ... Michael P Weekes
The human cytomegalovirus (HCMV) interactome systematically characterises high-confidence viral-viral and viral-host protein interactions in HCMV-infected cells, facilitating multiple novel insights into HCMV and herpesviral function.
A potentially useful cyanobacterial sulfated exopolysaccharide and its biosynthesis and regulation genes, which contribute to the laboratorial bloom formation, are elucidated for the first time among prokaryotes.
Electron microscopy on native membranes reveals the shape and potential function of protein machinery responsible for budding vesicles and viruses away from the cytoplasm.